A new manual and corresponding video are presented that show how to use Topspin 3 to process and analyze T1 relaxation measurement data to extract T1 values. The illustrations correspond to 1H data, but can be applied to normal pseudo-2D T1 data for other nuclei. This does NOT cover data acquisition – just analysis.
Very soon, all the instruments in the UChicago Chemistry NMR Facility will be equipped with autosamplers, including the manually-operated ones. Two questions may come to mind: How? Why?
The software running 500-3 and which will be running 600-1 is version 4.2.0 of Topspin. It works mostly the same as the Topspin we’ve been using, but there are some important differences to note. This post covers some of the key differences you’ll encounter right away.
500-1 is open, supporting walkup experiments in Searle. It’s outfitted with a different probe to provide better 13C sensitivity and capabilities of observing 31P, 11B, 195Pt, and more. Spectra are shown for a standard 10 mg/mL sample of carvone to provide a visual basis for comparison.
The new 400-2 is ready for use! With this upgrade, the spectrometer has transformed into an automated high-throughput engine for routine data acquisition. “Routine” now includes a variety of standard 2D experiments, plus 1D experiments for a growing assortment of NMR-active nuclei.
Major events took place in Week 1 of reopening, including a number of hardware and software upgrades to NMR systems. For Week 2, expect to continue using 400-1 for routine work. Other systems are actively being configured and upgraded in various ways, so please be patient.